In patients with neuropathy, neuropathic pain totally affects patients’ quality of life. Relieving pain is very essential to improve patient’s quality of life. Gabapentin relieves pain associated with neuropathy. Alpha lipoic acid, a powerful antioxidant, prevents nerve damage. Methylcobalamin regenerates neurons

Hyperhomocystinemia – a risk factor for CVD and thereby neuropathy, is kept under control with methycobalamin, folic acid and pyridoxine.Additionally, folic acid and pyridoxine can prevent reactive oxygen species formation. Hence, combination of these drugs is indicated in treatment of all peripheral neuropathies